Periodic Reporting for period 1 - G4-mtQSAR (Identifying new anti-cancer drugs by computational multi-target approaches targeting the Gquadruplex DNA)

G-Quadruplexes (G4s) are guanine-rich four-stranded nucleic acid structures, which are abundantly found in the promoter region of various oncogenes (cMYC, cKIT, KRAS, etc.) and in the telomeric region. Overexpression of these oncogenes and telomerase-induced sustained...