Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

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Authors: Mie Fabricius Pedersen, Tomasz Marcin Wróbel, Emil Märcher-Rørsted, Daniel Sejer Pedersen, Thor Christian Møller, Federica Gabriele, Henrik Pedersen, Dariusz Matosiuk, Simon Richard Foster, Michel Bouvier, Hans Bräuner-Osborne

Journal title: Neuropharmacology

Journal number: 166

Journal publisher: Pergamon Press Ltd.

Published year: 2020

Published pages: 107718

DOI identifier: 10.1016/j.neuropharm.2019.107718

ISSN: 0028-3908