Periodic Reporting for period 1 - INTERGLU (Dissecting mGlu5 receptor internalization pathways using genetic and pharmacological tools)

G protein-coupled receptors (GPCRs) are membrane proteins that are activated by a broad range of ligands and among the most abundant gene families in the human genome. GPCRs are involved in many important physiological processes and are the target of 30-40% of all marketed...