Periodic Reporting for period 1 - INTERGLP1 (Dissecting GLP-1 receptor internalization pathways using genetic and pharmacological tools)

The importance of the incretin hormone glucagon-like peptide-1 (GLP-1) in regulating post-prandial blood glucose levels has been known for decades and has led to the development of stable GLP-1 analogs for the treatment of type 2 diabetes. On the pancreatic ß-cell, GLP-1...