Periodic Reporting for period 1 - Onco-inflammation (Origin of genomic instability: Understanding the biological influence of inflammation in the initiation of pancreatic tumorigenesis)

Inflammation is suspected to be the first step leading to cancer due to alcohol consumption, tobacco smoking or air pollution between others. Little is known of how inflammation triggers genetic changes leading to tumorigenesis. In previous work I show that TGFb, a cytokine...