Periodic Reporting for period 1 - eXcape3D (Functional dissection of X-linked regulatory DNA: unravelling the impact of genome topology on transcriptional regulation)

The “eXcape3D” project was designed to understand how the genome looks and works by using X Chromosome Inactivation (XCI) as a model system. XCI ensures proper X-linked gene dosage between females (XX) and males (XY), is essential for female development, and results in...