Periodic Reporting for period 1 - Repro_organoid (Direct reprogramming of human astrocytes into functional neurons in cerebral organoids derived from genome edited hiPSCs)

The classical dogma of the central nervous system as an unchangeable entity has been refuted by the advent of direct lineage reprogramming of non-neuronal cells into neurons. During the last decade many studies including from the host laboratory have shown that brain-resident...