Periodic Reporting for period 1 - MIDAS (Predictive modelling of GPCR druggable allosteric sites)

G protein-coupled receptors (GPCRs) are the most successful druggable targets in the human genome. Up to 60 % of prescription drugs in the European Union act by modulating biological pathways involving GPCRs. GPCRs can be targeted by small molecules acting on allosteric...