Periodic Reporting for period 1 - R-FunSel (In vivo functional screening via CRISPR-Cas9 to systematically identify cardiomyocyte receptors as targets for the innovative therapies for myocardial infarction and heart failure)

There is an urgent need to develop new therapies for myocardial infarction to prevent cardiomyocyte loss, improve cardiac dysfunction and prevent eventual heart failure. All the currently available therapies are based on pato-physiological concepts developed in the mid-90’s...