Periodic Reporting for period 1 - MIRIC (Myeloid Cells: Investigating their Role for Immunotherapy in Cancer)

The checkpoint molecule Tim-3 is a co-inhibitory receptor that in recent years has been shown to mark the most severely “exhausted” or dysfunctional T cells. Largely stemming from work generated by my postdoctoral mentor, agents that interfere with Tim-3 signalling are now...