Periodic Reporting for period 1 - PARPin (Regulation of (ADP-ribosyl)ation signalling in the DNA damage response: elucidating the function of a novel PARP1/ARTD1 interactor)

The integrity of our DNA is constantly challenged by various types and sources of damaging agents that can cause genome instability, which is a common hallmark of many different cancer types and human pathologies. To protect DNA from damage, organisms have evolved a cellular...