Periodic Reporting for period 1 - Epigenome_embryo (How epigenetic reprogramming modulates 3D chromatin organization in totipotent embryos)

One of the most intriguing questions in biology is how a single cell (zygote) has the potential to give rise to all cell types of an organism, known as totipotency. Afterwards this potential is progressively lost along cleavage divisions to allow cell specification and...