Periodic Reporting for period 1 - AntiHelix (DNA helicases in genome maintenance: from molecular and cellular mechanisms to specific inhibitors as potential drugs)

The AntiHelix project aims to: 1) study the structure-function relationships of a group of bio-medically relevant DNA helicases; 2) analyse their role in genome stability maintenance pathways; 3) discover small molecule inhibitors of these enzymes, which have the potential to...