Periodic Reporting for period 1 - PrediKSion (PrediKSion: An evolutionary guided and experimentally validated computational pipeline to unravel new polyketide synthase functionality)

Bacterial multimodular polyketide synthases (PKSs) are giant enzymes that generate a wide range of therapeutically important but synthetically challenging natural products. These natural products have found widespread use as, e.g., antibiotics, anticancer therapeutics and...