Periodic Reporting for period 1 - GlycoPCs (How do Pharmacological Chaperones work? Molecular basis of the actions of glycomimetics on keyglycosidases involved in lysosomal storage disorders)

Numerous glycosidic enzymes present in the lysosome are required for metabolizing a wide variety of molecules, such as glycoproteins, glycolipids and oligosaccharides. These enzymes are synthesized in the endoplasmic reticulum and are transferred to the lysosome where they...