Standardized protocols for the formulation of tunable nanoparticles with defined properties

WP 3 aims to explore the potential of new nanoparticle manufacturing methods. This deliverable will be achieved through: Task 3.1 & Task 3.3 - The production, in-vitro characterization (size, morphology, drug loading efficiency) and optimization of nanoparticles loaded with drugs of different solubility and permeability properties (e.g. selected from the 4 classes of the Biopharmaceutical Classification System (BCS) for poorly soluble model drugs). Test formulations for model biopharmaceuticals (e.g. insulin) will also be prepared and characterized.