Periodic Reporting for period 1 - PDA_TGFb (TGF-beta mediated crosstalk between cancer (stem) cells and tumor microenvironment in pancreatic cancer metastasis)

Pancreatic ductal adenocarcinoma (PDAC) is the fourth-leading cause of cancer-related death in the world, with a 5-year survival rate of less than 5%. Chemotherapy resistance and tumour relapse are two unresolved problems in PDAC treatment. Cancer stem cells (CSCs) are key...