Periodic Reporting for period 1 - Ancestral (Structural and biochemical studies of an ancestral enzyme with dual dehalogenase and luciferase activity)

Haloalkane dehalogenases (HLDs), which catalyse the cleavage of the carbon-halogen bond of organohalogen compounds, are recognized as key tools in many industrial and biotechnological processes. Interestingly, HLD enzymes display remarkable sequence and structural similarity...