Periodic Reporting for period 1 - NEVADA (Novel microengineered environments for mouse embryonic stem cell (mESC) differentiation towards cardiomyocytes)

Many forms of heart disease are associated with a decrease in the number of functional cardiomyocytes (CMs). Since the proliferative capacity of CMs decreases significantly in postnatal life, elucidation of the molecular mechanisms that govern cell pluripotent state and...