Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome

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Authors: Marco Borgogno, Annalisa Savardi, Jacopo Manigrasso, Alessandra Turci, Corinne Portioli, Giuliana Ottonello, Sine Mandrup Bertozzi, Andrea Armirotti, Andrea Contestabile, Laura Cancedda, Marco De Vivo

Journal title: Journal of Medicinal Chemistry

Journal number: 64/14

Journal publisher: American Chemical Society

Published year: 2021

Published pages: 10203-10229

DOI identifier: 10.1021/acs.jmedchem.1c00603

ISSN: 0022-2623