Periodic Reporting for period 1 - FUSEDESIGN (Model-guided design of a stabilized pre-fusion class III viral fusogen, rabies virus glycoprotein)

Summary
Multiple human pathogens are enveloped viruses that require specific membrane proteins (also known as fusogens) to perform the first stage of viral infection, namely fusion of viral and host membranes. Often such fusogens invoke strong immune responses in infected hosts and...