Cyclotron production and mass-separation of 47/48/49Sc

Large scale production of a beta-/gamma emitter radioisotope for therapy using a middle sized high-current cyclotron and the CERN-MEDICIS mass separation system Objectives: feasibility study for a large scale production of selected isotopes using a middle sized high current cyclotron and the CERN-MEDICIS mass separation system Expected Results: Perform a explorative study based on theoretical analysis and Monte Carlo simulations in order to identify radioisotopes with favourable characteristics, namely: β- spectrum for therapy; γ emission for SPECT imaging; half-life for logistics and clinical use, corresponding β+ (positron) emitting isotope to be used as companion diagnostic agent; favourable chemistry for targeted radiometabolic therapy suitability; effective production yield, for 30-70 MeV protons, target feasibility, effective extraction yield with the CERN-MEDICIS mass separation system.)