Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation

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Authors: Gemma Fisher, Marina Corbella, Magnus S. Alphey, John Nicholson, Benjamin J. Read, Shina C. L. Kamerlin, Rafael G. da Silva

Journal title: Nature Communications

Journal number: 13

Journal publisher: Nature Publishing Group

Published year: 2022

DOI identifier: 10.1038/s41467-022-34960-9

ISSN: 2041-1723