Periodic Reporting for period 1 - MetEpiC (P53-dependent Metabolic and Epigenetic Reprogramming in Carcinogenesis)

Cancer is a multifactorial and complex disease, but some alterations are frequently observed in tumors. Mutations of the tumor suppressor gene TP53, a guardian of our cells, are the most frequent alterations in cancers cells, with about half of tumors harboring this mutational...