Periodic Reporting for period 1 - NEURINFDNA (Neuronal DNA double strand breaks as novel epigenetic actors: roles in cognition, health and neuro-inflammatory diseases)

Cognitive deficits are manifested years prior detecting neuronal loss in neurodegenerative diseases or during persistent infections of the central nervous system (CNS). Accumulating evidence show that epigenetic alterations contribute to neuronal dysfunction, as they change...