High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

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Authors: Nadia Arang, Simone Lubrano, Michele Ceribelli, Damiano C Rigiracciolo, Robert Saddawi-Konefka, Farhoud Faraji, Sydney I Ramirez, Daehwan Kim, Frances A Tosto, Erica Stevenson, Yuan Zhou, Zhiyong Wang, Julius Bogomolovas, Alfredo A Molinolo, Danielle L Swaney, Nevan J Krogan, Jing Yang, Silvia Coma, Jonathan A Pachter, Andrew E Aplin, Dario R Alessi, Craig J Thomas, J Silvio Gutkind

Journal title: Cell Reports Medicine

Journal number: 2023 Nov 21

Journal publisher: Elsevier

Published year: 2023

Published pages: 4(11):101244

DOI identifier: 10.1016/j.xcrm.2023.101244

ISSN: 2666-3791