Periodic Reporting for period 1 - INTEGRIN REGULATION (Functional analysis of the kinome and phosphatome as determinants of integrin phosphorylation in cancer)

Cancer dissemination from a primary tumour is a complex process that is mediated by cell-cell and cell-ECM (extracellular matrix) interactions. Integrin adhesion receptors are key signalling molecules that mediate the extracellular binding of ECM by cells, and the respective...