Periodic Reporting for period 1 - TITINmap (Towards Uncovering the Splicing Code of the Gigantic Gene Titin in Familial Dilated Cardiomyopathy)

Titin is the largest protein of the human body and critical for the contraction of heart muscle cells. It is mutated in 30% of patients with familial dilated cardiomyopathy (DCM), a common heart disease that is a global threat to the aging society. RBM20, which is also mutated...