Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile

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Authors: Edurne Rujas, Daniel P. Leaman, Sara Insausti, Pablo Carravilla, Miguel García-Porras, Eneko Largo, Izaskun Morillo, Rubén Sánchez-Eugenia, Lei Zhang, Hong Cui Ibon Iloro, Félix Elortza, Jean-Philippe Julien, Christian Eggeling, Michael B.Zwick, Jose M.M. Caaveiro, José L. Nieva

Journal title: iScience

Journal publisher: Elsevier Inc.

Published year: 2021

DOI identifier: 10.1016/j.isci.2021.102987

ISSN: 2589-0042