Periodic Reporting for period 1 - NeuroRhomboid (Discovering the signalling pathways and physiology of active rhomboid proteases in the brain)

Protease enzymes catalyse irreversible post-translational modifications that control many distinct cellular processes. An important class are intramembrane proteases, which have catalytic activity that is confined within the lipid bilayer. Intramembrane proteases function to...