Periodic Reporting for period 1 - hsPCF-FRET (Real-time characterisation of neuropeptide binding to a membrane receptor involved in pain and ischemic stroke)

One way for neurons to communicate with each other is through highly localised changes in brain tissue pH that activate acid-sensing ion channels (ASIC1a). The subtype ASIC1a plays a significant role in detecting low pH and makes essential contributions to learning and memory...