Periodic Reporting for period 2 - EpiSyStem (Epigenetics and System Biology of Stem cells and Reprogramming)

In eukaryotic cells, DNA is tightly packaged as chromatin in a form of nucleosomes, comprised of 147 bp of DNA wrapped around two copies each of the core histones H2A, H2B, H3 and H4. Nucleosomes are separated by linker DNA, bound by a linker histone, H1. Chromatin structure...