Periodic Reporting for period 1 - TransSplicHD (Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease.)

Huntington's disease (HD) is a hereditary, fatal neurodegenerative disorder, mainly affecting people in mid-life. Although more than 20 years have passed since the discovery of the disease-causing genetic mutation - an expanded DNA repeat at the tip of chromosome 4 -, the...