Periodic Reporting for period 2 - BURK-6 (Investigation of the Type VI secretion system-associated toxins of Burkholderia thailandensis)

Problem addressed: Burkholderia pseudomallei causes melioidosis, a neglected tropical infectious disease, which treatment is complicated by long phases of latency and a high antibiotic resistance. Bacterial secretion systems, which act as small syringes, play a central role in...