Periodic Reporting for period 1 - IMMUNO-RQC (Role of Listerin ubiquitin ligase in MHC-I antigen presentation)

Mammalian cells present their proteome content to the adaptive immune system through the display of peptides on MHC-I complexes. This allows for CD8+ T cells to selectively recognize and kill cells that present non-self antigens, for example due to viral infection or cancer...