Periodic Reporting for period 1 - SingleCellAI (Deep-learning models of CRISPR-engineered cells define a rulebook of cellular transdifferentiation)

Over-expression of just a few transcription factors (TFs) can transform a fully differentiated cell into a state of induced pluripotency (iPS). Even more astoundingly, a similar strategy can perform cellular transdifferentiation, i.e. direct conversion of a cell from one type...