Periodic Reporting for period 1 - MADMpancreas (Using the precision mouse genetic tool MADM to elucidate the role of EGFR in directing beta cell differentiation and pancreatic morphogenesis)

The pancreas houses two physiologically distinct compartments within one organ. The hormone-producing endocrine cells of the islets and the tubular ductal system of the exocrine pancreas share a common developmental progenitor. Recent work from the Semb group implicated Egfr...