Periodic Reporting for period 1 - TRIBBLES (Characterizing the clinical relevance and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma)

Malignant melanoma is a highly aggressive cancer that arises from the transformation of melanocytes, the pigment-producing cells within the basal epidermal layer in human skin. Malignant melanoma accounts for only 5% of all skin cancers, yet is responsible for 80% of skin...