Periodic Reporting for period 1 - UNBRACE (Investigating the Role of the Unfolded Protein Response as a Novel Targetable Pathway in BRAF Mutant Colorectal Cancer)

Pancreatic ductal adenocarcinoma (PDAC) accounts for approximately 90% of all cases of pancreatic cancer. Pancreatic stellate cells (PSCs) are the most prominent cell type in the PDAC stroma, accounting for around 50% of the tumour microenvironment. Interestingly, PSCs show...