In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy

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Authors: Oscar Escalona-Rayo , Ye Zeng , Renzo A. Knol , Thomas J.F. Kock , Dennis Aschmann , Bram Slütter , Alexander Kros

Journal title: Biomedicine & Pharmacotherapy

Journal number: vol 165

Journal publisher: Elsevier Masson SAS

Published year: 2023

DOI identifier: 10.1016/j.biopha.2023.115065