Periodic Reporting for period 1 - Prion Respiration (The Role of Complex I Assembly Factors during Prion Diseases: Insights into Mitochondrial Neurobiology)

Mitochondria have a crucial role in cell survival and apoptosis, in particular in long-lived cells such as neurons. Mitochondria generate energetic potential through respiratory complexes I to IV, which constitute the electron transport chain. Mitochondrial integrity declines...