Periodic Reporting for period 1 - CF_struct (High-Resolution X-ray Structures of Full-Length Cystic Fibrosis Transmembrane Conductance Regulator)

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), the protein implicated in cystic fibrosis (CF), has approximately 2,000 single mutations that cause dysfunction of the protein. Defective CFTR causes a thickening of mucus leading to infections, lowered quality...