Periodic Reporting for period 1 - Als-on-a-chip (A tissue-on-a-chip platform for systems-level studies of ALS pathology and drug screening)

Amyotrophic Lateral Sclerosis (ALS) is a complex disease, characterized by diverse pathology that causes progressive motor neuron death. Unfortunately, most ALS patients die within 5 years. The single FDA-approved ALS drug (riluzole) has modest effects, so there is urgent need...