Periodic Reporting for period 1 - Huntingtin hPSC (Unraveling huntingtin function in cortical and striatal human development)

Huntington's disease (HD) is a rare neurodegenerative autosomic dominant disorder which main symptoms include severe motor dysfunction and cognitive deficits. Genetically, HD is a monogenic disorder driven by an expanded CAG repeat mutation located at the 5' end of the...