Periodic Reporting for period 1 - MitSyn (Alpha-synuclein and mitochondrial dysfunction: key links between Gaucher’s disease and Parkinson’s?)

Mutations of a lysosomal enzyme termed glucocerebrosidase (GCase, encoded by the gene GBA) cause Gaucher’s disease (GD) but also have a strong association with Parkinson’s disease (PD). This enzyme is responsible for the recycling of a special class of lipids called...