Periodic Reporting for period 1 - CFZEBRA (Balancing the immune response in cystic fibrosis: using zebrafish models of infection and inflammation to uncover new therapeutic approaches)

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR). In people with CF, the defect in CFTR gene causes a severe defect of mucociliary clearance with the development of thick mucus, which forms a protected niche for bacterial growth...