Periodic Reporting for period 1 - NMRSIGN (NMR insights on the soluble Guanylyl Cyclase conformational dynamics to illuminate the SIGNaling pathway)

Gas-sensing proteins play an important role in mediating biological events. Soluble guanylate cyclase (sGC) is activated when nitric oxide (NO) binds to heme Fe of sGC, resulting to the stimulation of the cyclization of guanosine 5- triphosphate (GTP) to the second messenger...