Periodic Reporting for period 2 - ChondUb (Identification and characterisation of novel WWP2 substrates and their role in chondrogenesis and osteoarthritis)

Osteoarthritis (OA), which is characterised by progressive cartilage degradation, is the most common form of arthritis affecting more than 10% of the EU population over 60 years of age. The cause of OA is still not known and there is no cure available. The current treatment...