Periodic Reporting for period 1 - EGFR-Activ (Epidermal growth factor receptor (EGFR) activation by cytohesins - Structural Insights)

In humans, EGFR’s incorrect signalling is associated with neurodegenerative diseases and a number of cancers. Thus, mechanisms that modulate the activation of these receptors are high profile drug targets. However, many of the drugs in use cause a variety of skin toxicities...