Periodic Reporting for period 1 - ParaplegiaAxonsER (Functional interactions between endoplasmic reticulum and mitochondria in Drosophila axons)

Hereditary Spastic Paraplegias (HSPs) are a group of disorders characterised by lower limb spasticity and weakness, caused by selective degeneration of motor neurons. Whilst there are many genes implicated in HSP, the most commonly mutated group of genes are those involved in...